PT - JOURNAL ARTICLE AU - Vegunta, Suneela AU - Mussallem, Dawn M. AU - Kaur, Aparna S. AU - Pruthi, Sandhya AU - Klassen, Christine L. TI - Atypical hyperplasia of the breast: Clinical cases and management strategies AID - 10.3949/ccjm.90a.22098 DP - 2023 Jul 01 TA - Cleveland Clinic Journal of Medicine PG - 423--431 VI - 90 IP - 7 4099 - http://www.ccjm.org/content/90/7/423.short 4100 - http://www.ccjm.org/content/90/7/423.full SO - Cleve Clin J Med2023 Jul 01; 90 AB - Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atypical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.