RT Journal Article SR Electronic T1 Atypical hyperplasia of the breast: Clinical cases and management strategies JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 423 OP 431 DO 10.3949/ccjm.90a.22098 VO 90 IS 7 A1 Vegunta, Suneela A1 Mussallem, Dawn M. A1 Kaur, Aparna S. A1 Pruthi, Sandhya A1 Klassen, Christine L. YR 2023 UL http://www.ccjm.org/content/90/7/423.abstract AB Atypical hyperplasia of the breast is a histopathologic lesion identified incidentally on image-guided breast biopsy. It is associated with a substantial increase in lifetime risk for breast cancer. Clinicians should counsel women with atypical hyperplasia regarding risk-reducing strategies, which include preventive endocrine therapy options, enhanced surveillance imaging, and lifestyle modifications. In this review, we describe 5 different but common clinical case scenarios for atypical hyperplasia of the breast and review management strategies for each scenario.