PT  - JOURNAL ARTICLE
AU  - Braghieri, Lorenzo
AU  - Badwan, Osamah Z.
AU  - Skoza, Warren
AU  - Fares, Maan
AU  - Menon, Venu
TI  - Evaluating troponin elevation in patients with chronic kidney disease and suspected acute coronary syndrome
AID  - 10.3949/ccjm.90a.23012
DP  - 2023 Aug 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 483--489
VI  - 90
IP  - 8
4099  - http://www.ccjm.org/content/90/8/483.short
4100  - http://www.ccjm.org/content/90/8/483.full
SO  - Cleve Clin J Med2023 Aug 01; 90
AB  - Many patients with chronic kidney disease have chronically elevated cardiac troponin levels, and if they present with symptoms suggesting an acute coronary syndrome, it is often difficult to determine if this is the correct diagnosis. This article briefly reviews the major challenges in diagnosing acute coronary syndrome in patients with chronic kidney disease, describes the mechanisms and prognostic significance of troponin elevation in chronic kidney disease, and provides a diagnostic algorithm to risk-stratify patients with chronic kidney disease who have troponin elevation and suspected acute coronary syndrome.