RT Journal Article SR Electronic T1 Evaluating troponin elevation in patients with chronic kidney disease and suspected acute coronary syndrome JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 483 OP 489 DO 10.3949/ccjm.90a.23012 VO 90 IS 8 A1 Braghieri, Lorenzo A1 Badwan, Osamah Z. A1 Skoza, Warren A1 Fares, Maan A1 Menon, Venu YR 2023 UL http://www.ccjm.org/content/90/8/483.abstract AB Many patients with chronic kidney disease have chronically elevated cardiac troponin levels, and if they present with symptoms suggesting an acute coronary syndrome, it is often difficult to determine if this is the correct diagnosis. This article briefly reviews the major challenges in diagnosing acute coronary syndrome in patients with chronic kidney disease, describes the mechanisms and prognostic significance of troponin elevation in chronic kidney disease, and provides a diagnostic algorithm to risk-stratify patients with chronic kidney disease who have troponin elevation and suspected acute coronary syndrome.