RT Journal Article SR Electronic T1 Evaluating a low anion gap: A practical approach JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 619 OP 623 DO 10.3949/ccjm.90a.23035 VO 90 IS 10 A1 Haber, Lawrence A. A1 Dhaliwal, Gurpreet A1 Lo, Lowell A1 Rizzuto, Gabrielle YR 2023 UL http://www.ccjm.org/content/90/10/619.abstract AB In teaching and in practice, little attention is given to a low anion gap. This oversight can result in a missed opportunity to diagnose acute or chronic disorders requiring treatment. In this article, we review the constituents of the anion gap, build a differential diagnosis for a low anion gap using case examples, and provide a stepwise approach to diagnostic testing to evaluate this abnormal finding.