PT - JOURNAL ARTICLE AU - Geisberg, Carrie AU - Butler, Javed TI - Addressing the challenges of cardiorenal syndrome DP - 2006 May 01 TA - Cleveland Clinic Journal of Medicine PG - 485--491 VI - 73 IP - 5 4099 - http://www.ccjm.org/content/73/5/485.short 4100 - http://www.ccjm.org/content/73/5/485.full SO - Cleve Clin J Med2006 May 01; 73 AB - In heart failure, as the heart gets worse, often so do the kidneys, complicating the treatment of heart failure and worsening the prognosis. This article addresses challenges in the use of diuretics, angiotensin-converting enzyme (ACE) inhibitors, and other therapies in the cardiorenal syndrome, as well as novel therapies that hold promise, such as arginine vasopressin antagonists, adenosine A1 receptor antagonists, and ultrafiltration.