PT  - JOURNAL ARTICLE
AU  - Khazaaleh, Shrouq
AU  - Alomari, Mohammad
AU  - Rashid, Mamoon Ur
AU  - Castaneda, Daniel
AU  - Castro, Fernando J.
TI  - Gastric intestinal metaplasia and gastric cancer prevention: Watchful waiting
AID  - 10.3949/ccjm.91a.23015
DP  - 2024 Jan 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 33--39
VI  - 91
IP  - 1
4099  - http://www.ccjm.org/content/91/1/33.short
4100  - http://www.ccjm.org/content/91/1/33.full
SO  - Cleve Clin J Med2024 Jan 01; 91
AB  - Gastric intestinal metaplasia (GIM), a common histologic finding, is associated with increased risk of gastric cancer, and GIM associated with Helicobacter pylori infection is classified as an environmental metaplastic atrophic gastritis. Patients may be asymptomatic or present with various dyspeptic symptoms. Autoimmune metaplastic atrophic gastritis is a less common but important cause of chronic gastritis. The Correa cascade describes the evolution of precancerous mucosal changes that lead to development of GIM, with differentiation of 2 histologic types of GIM (complete and incomplete) and the consequences of each type. The risk of progression to malignancy is higher with incomplete GIM. It is also higher for those who immigrate from regions with a high incidence of H pylori infection to areas where the incidence is low. Guidelines regarding endoscopic management of GIM vary by geographic region.