RT Journal Article
SR Electronic
T1 Gastric intestinal metaplasia and gastric cancer prevention: Watchful waiting
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 33
OP 39
DO 10.3949/ccjm.91a.23015
VO 91
IS 1
A1 Khazaaleh, Shrouq
A1 Alomari, Mohammad
A1 Rashid, Mamoon Ur
A1 Castaneda, Daniel
A1 Castro, Fernando J.
YR 2024
UL http://www.ccjm.org/content/91/1/33.abstract
AB Gastric intestinal metaplasia (GIM), a common histologic finding, is associated with increased risk of gastric cancer, and GIM associated with Helicobacter pylori infection is classified as an environmental metaplastic atrophic gastritis. Patients may be asymptomatic or present with various dyspeptic symptoms. Autoimmune metaplastic atrophic gastritis is a less common but important cause of chronic gastritis. The Correa cascade describes the evolution of precancerous mucosal changes that lead to development of GIM, with differentiation of 2 histologic types of GIM (complete and incomplete) and the consequences of each type. The risk of progression to malignancy is higher with incomplete GIM. It is also higher for those who immigrate from regions with a high incidence of H pylori infection to areas where the incidence is low. Guidelines regarding endoscopic management of GIM vary by geographic region.