PT - JOURNAL ARTICLE AU - Hoogwerf, Byron J. TI - Exenatide and pramlintide: New glucose-lowering agents for treating diabetes mellitus DP - 2006 May 01 TA - Cleveland Clinic Journal of Medicine PG - 477--484 VI - 73 IP - 5 4099 - http://www.ccjm.org/content/73/5/477.short 4100 - http://www.ccjm.org/content/73/5/477.full SO - Cleve Clin J Med2006 May 01; 73 AB - Insulin is not the only hormone that regulates plasma glucose levels. Glucagon-like peptide 1 (GLP-1), produced in the small intestine, and amylin, produced by beta cells in the pancreas, also have glucose-lowering effects. Synthetic analogues of these hormones are now available for clinical use.