RT Journal Article SR Electronic T1 Exenatide and pramlintide: New glucose-lowering agents for treating diabetes mellitus JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 477 OP 484 VO 73 IS 5 A1 Hoogwerf, Byron J. YR 2006 UL http://www.ccjm.org/content/73/5/477.abstract AB Insulin is not the only hormone that regulates plasma glucose levels. Glucagon-like peptide 1 (GLP-1), produced in the small intestine, and amylin, produced by beta cells in the pancreas, also have glucose-lowering effects. Synthetic analogues of these hormones are now available for clinical use.