RT Journal Article SR Electronic T1 Medical management of benign prostatic hyperplasia JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 163 OP 170 DO 10.3949/ccjm.91a.23027 VO 91 IS 3 A1 Haile, Eiftu S. A1 Sotimehin, Ayodeji E. A1 Gill, Bradley C. YR 2024 UL http://www.ccjm.org/content/91/3/163.abstract AB Medical management of benign prostatic hyperplasia (BPH) has progressed gradually in recent years and remains the starting point for most symptomatic patients seeking treatment. Beyond well-known alpha-blockers and 5-alpha reductase inhibitors, there is growing evidence for the use of phosphodiesterase-5 inhibitors and beta-3 agonists in managing the condition, which may afford additional relief of “bothersome” symptoms in some patients. This review details contemporary medical management of BPH with an emphasis on the indications for certain classes of pharmacotherapy and their relative benefits and side effects. Surgical and procedural treatment of BPH is covered in a separate review.