PT  - JOURNAL ARTICLE
AU  - Davidson, Michael B.
AU  - Mehta, Adi E.
AU  - Siraj, Elias S.
TI  - Inhaled human insulin: An inspiration for patients with diabetes mellitus?
DP  - 2006 Jun 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 569--578
VI  - 73
IP  - 6
4099  - http://www.ccjm.org/content/73/6/569.short
4100  - http://www.ccjm.org/content/73/6/569.full
SO  - Cleve Clin J Med2006 Jun 01; 73
AB  - Inhaled insulin offers a novel option for controlling blood glucose levels in type 1 and type 2 diabetes, obviating the need for multiple daily injections. The first of several delivery systems, insulin Exubera, was recently approved by the US Food and Drug Administration (FDA). However, questions remain regarding its efficacy, cost-effectiveness, and possible deleterious effects on pulmonary function. This review will discuss the pharmacology, efficacy, important clinical trials, and practical aspects of inhaled insulin, and potential concerns associated with its use.