PT  - JOURNAL ARTICLE
AU  - Ziyadeh, Farah
AU  - Mauer, Yael
TI  - Management of lower-extremity venous thromboembolism: An updated review
AID  - 10.3949/ccjm.91a.22090
DP  - 2024 Apr 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 229--235
VI  - 91
IP  - 4
4099  - http://www.ccjm.org/content/91/4/229.short
4100  - http://www.ccjm.org/content/91/4/229.full
SO  - Cleve Clin J Med2024 Apr 01; 91
AB  - According to the 2021 updated guidelines of the American College of Chest Physicians, the location of venous thromboembolism, the severity of symptoms, the risk of thrombus extension vs that of bleeding, and comorbidities all affect the decision to treat, the choice of anti-thrombotic agent, and the duration of therapy. In patients with isolated distal deep vein thrombosis without high-risk features, monitoring progression is recommended over initiating anticoagulation. However, treatment of proximal deep vein thrombosis with anticoagulation is strongly recommended by the guidelines. More evidence now supports the treatment of superficial vein thrombosis with anticoagulation in high-risk patients.