PT - JOURNAL ARTICLE AU - Iyer, Tara K. AU - Fiffick, Alexa N. AU - Batur, Pelin TI - Nonhormone therapies for vasomotor symptom management AID - 10.3949/ccjm.91a.23067 DP - 2024 Apr 01 TA - Cleveland Clinic Journal of Medicine PG - 237--244 VI - 91 IP - 4 4099 - http://www.ccjm.org/content/91/4/237.short 4100 - http://www.ccjm.org/content/91/4/237.full SO - Cleve Clin J Med2024 Apr 01; 91 AB - Vasomotor symptoms (VMS) are associated with adverse health consequences and can cause significant morbidity for postmenopausal women. Although hormone therapy remains the gold standard of VMS treatment in menopausal women, some women have contraindications to or may choose not to take hormone therapy. This article provides an up-to-date overview of the current evidence-based nonhormone therapies available for managing VMS. Evidence supporting various treatment options is reviewed, including lifestyle interventions, mind-body therapies, procedures, pharmacologic agents, and emerging therapies, such as neurokinin-receptor antagonists. The efficacy, safety, and clinical use of these treatments are detailed, offering insights for clinicians to make informed decisions in menopausal VMS management.