RT Journal Article SR Electronic T1 SGLT-2 inhibitors in heart failure and chronic kidney disease: A review for internists JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 415 OP 423 DO 10.3949/ccjm.91a.23093 VO 91 IS 7 A1 Jaswaney, Rahul A1 Sokoloff, Samantha A1 Rakita, Val A1 Rubin, Daniel J. YR 2024 UL http://www.ccjm.org/content/91/7/415.abstract AB Despite current therapies, heart failure and chronic kidney disease continue to be major causes of morbidity and mortality. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors have recently become standard-of-care therapy for these conditions. This review summarizes important randomized controlled trials of SGLT-2 inhibitors and guidelines for using these agents in patients with heart failure and chronic kidney disease in both clinic and hospital settings.