PT - JOURNAL ARTICLE AU - Francis, Gary AU - Tang, W.H. Wilson TI - New approaches to detect and manage edema and renal insufficiency in heart failure DP - 2006 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - S14--S19 VI - 73 IP - 6 suppl 2 4099 - http://www.ccjm.org/content/73/6_suppl_2/S14.short 4100 - http://www.ccjm.org/content/73/6_suppl_2/S14.full SO - Cleve Clin J Med2006 Jun 01; 73 AB - Earlier detection of edema and renal insufficiency, before overt decompensation, is fundamental to further advances in altering the natural history of heart failure. Progress is being made in the earlier detection of these complications through the use of new devices that monitor for hemodynamic compromise and through monitoring of select cardiac and renal biomarkers. In addition, diuretic-sparing approaches to heart failure management, novel drug classes, new devices, and nonpharmacologic therapies are emerging to reduce reliance on diuretic therapy and manage edema with less renal compromise.