PT - JOURNAL ARTICLE AU - Lundholm, Michelle D. AU - Ambalavanan, Jayachidambaram AU - Rao, Pratibha PR TI - Primary adrenal insufficiency in adults: When to suspect, how to diagnose and manage AID - 10.3949/ccjm.91a.23072 DP - 2024 Sep 01 TA - Cleveland Clinic Journal of Medicine PG - 553--562 VI - 91 IP - 9 4099 - http://www.ccjm.org/content/91/9/553.short 4100 - http://www.ccjm.org/content/91/9/553.full SO - Cleve Clin J Med2024 Sep 01; 91 AB - Primary adrenal insufficiency is rare but serious; it puts patients at risk of acute decompensation and adrenal crisis due to insufficient cortisol and aldosterone production. Further, its diagnosis is often delayed, or it is mistaken for secondary adrenal insufficiency, which can have life-threatening consequences. Early recognition and appropriate treatment can greatly improve patient outcomes and quality of life.