RT Journal Article SR Electronic T1 Primary adrenal insufficiency in adults: When to suspect, how to diagnose and manage JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 553 OP 562 DO 10.3949/ccjm.91a.23072 VO 91 IS 9 A1 Lundholm, Michelle D. A1 Ambalavanan, Jayachidambaram A1 Rao, Pratibha PR YR 2024 UL http://www.ccjm.org/content/91/9/553.abstract AB Primary adrenal insufficiency is rare but serious; it puts patients at risk of acute decompensation and adrenal crisis due to insufficient cortisol and aldosterone production. Further, its diagnosis is often delayed, or it is mistaken for secondary adrenal insufficiency, which can have life-threatening consequences. Early recognition and appropriate treatment can greatly improve patient outcomes and quality of life.