PT  - JOURNAL ARTICLE
AU  - Francis, Gary
TI  - Acute decompensated heart failure: The cardiorenal syndrome
DP  - 2006 Jun 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S8--S13
VI  - 73
IP  - 6 suppl 2
4099  - http://www.ccjm.org/content/73/6_suppl_2/S8.short
4100  - http://www.ccjm.org/content/73/6_suppl_2/S8.full
SO  - Cleve Clin J Med2006 Jun 01; 73
AB  - The cardiorenal syndrome is not well understood, and a uniform definition is lacking. Worsening renal function as determined by a decline in creatinine clearance in patients with decompensated heart failure is an identifier of patients with this syndrome. Treatment is a challenge. Diuretic therapy is valuable in treating congestion but may worsen renal function. Patients with decompensated heart failure are often refractory to diuretics, in which case higher doses must be used or alternate methods explored to reduce salt and water.