PT - JOURNAL ARTICLE AU - Clifford, Alison H. TI - Incidentally detected noninfectious thoracic aortitis: A clinical approach AID - 10.3949/ccjm.91a.24030 DP - 2024 Oct 01 TA - Cleveland Clinic Journal of Medicine PG - 621--633 VI - 91 IP - 10 4099 - http://www.ccjm.org/content/91/10/621.short 4100 - http://www.ccjm.org/content/91/10/621.full SO - Cleve Clin J Med2024 Oct 01; 91 AB - Noninfectious aortitis is occasionally detected incidentally, either on imaging or on histopathologic review after open thoracic aortic surgery. It can present as a clinically asymptomatic, seemingly focal lesion, as diffuse inflammation throughout several aortic segments but sparing the branch vessels, or as a manifestation of a widespread systemic condition. Treatment differs based on etiology, so once identified, all patients with aortitis need a thorough evaluation, laboratory tests, complete large-vessel imaging, and a referral to a vasculitis expert. All patients with aortitis are at high risk of future vascular complications and should be followed with serial clinical evaluations and imaging.