PT - JOURNAL ARTICLE AU - Gold, Rebecca S. AU - Williams, Meagan AU - Wainstein, Heather M. TI - Cervical cancer screening in high-risk patients: Clinical challenges in primary care AID - 10.3949/ccjm.91a.24023 DP - 2024 Nov 01 TA - Cleveland Clinic Journal of Medicine PG - 693--703 VI - 91 IP - 11 4099 - http://www.ccjm.org/content/91/11/693.short 4100 - http://www.ccjm.org/content/91/11/693.full SO - Cleve Clin J Med2024 Nov 01; 91 AB - The risk of developing cervical cancer is not equal across populations—individual health history, economic, political, and societal factors influence cervical cancer risk. Certain health conditions, including human immunodeficiency virus (HIV) infection, immunosuppression, and history of high-grade cervical dysplasia, are associated with higher cervical cancer risk and warrant distinct screening, surveillance, and management guidelines. It is imperative for clinicians to recognize high-risk groups and apply appropriate corresponding guidelines. However, this can be difficult in practice, as recommendations regularly evolve. This review offers up-to-date guidance in a case-based format on cervical cancer screening, surveillance, and management for high-risk patients.