RT Journal Article SR Electronic T1 Cervical cancer screening in high-risk patients: Clinical challenges in primary care JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 693 OP 703 DO 10.3949/ccjm.91a.24023 VO 91 IS 11 A1 Gold, Rebecca S. A1 Williams, Meagan A1 Wainstein, Heather M. YR 2024 UL http://www.ccjm.org/content/91/11/693.abstract AB The risk of developing cervical cancer is not equal across populations—individual health history, economic, political, and societal factors influence cervical cancer risk. Certain health conditions, including human immunodeficiency virus (HIV) infection, immunosuppression, and history of high-grade cervical dysplasia, are associated with higher cervical cancer risk and warrant distinct screening, surveillance, and management guidelines. It is imperative for clinicians to recognize high-risk groups and apply appropriate corresponding guidelines. However, this can be difficult in practice, as recommendations regularly evolve. This review offers up-to-date guidance in a case-based format on cervical cancer screening, surveillance, and management for high-risk patients.