PT - JOURNAL ARTICLE AU - Collins, Gregory B. AU - McAllister, Mark S. AU - Adury, Kamala TI - Drug adjuncts for treating alcohol dependence DP - 2006 Jul 01 TA - Cleveland Clinic Journal of Medicine PG - 641--656 VI - 73 IP - 7 4099 - http://www.ccjm.org/content/73/7/641.short 4100 - http://www.ccjm.org/content/73/7/641.full SO - Cleve Clin J Med2006 Jul 01; 73 AB - Three drugs are approved by the US Food and Drug Administration for treating alcoholism: disulfiram, naltrexone, and acamprosate. Drugs approved for other indications that are being used experimentally or “off-label” include nalmafene, topiramate, and ondansetron. As we learn more about the pathophysiologic basis of alcoholism, it is hoped that novel drugs can be developed to help people with alcohol dependence achieve abstinence, and as a result, curb alcohol-related morbidity.