RT Journal Article
SR Electronic
T1 Drug adjuncts for treating alcohol dependence
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 641
OP 656
VO 73
IS 7
A1 Collins, Gregory B.
A1 McAllister, Mark S.
A1 Adury, Kamala
YR 2006
UL http://www.ccjm.org/content/73/7/641.abstract
AB Three drugs are approved by the US Food and Drug Administration for treating alcoholism: disulfiram, naltrexone, and acamprosate. Drugs approved for other indications that are being used experimentally or “off-label” include nalmafene, topiramate, and ondansetron. As we learn more about the pathophysiologic basis of alcoholism, it is hoped that novel drugs can be developed to help people with alcohol dependence achieve abstinence, and as a result, curb alcohol-related morbidity.