PT  - JOURNAL ARTICLE
AU  - Xu, Risheng
AU  - Abate, Nicola
AU  - Ram, Nalini
AU  - Little, Kristina
TI  - Most elderly patients with subclinical hypothyroidism do not need to be treated
AID  - 10.3949/ccjm.92a.24098
DP  - 2025 Apr 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 221--231
VI  - 92
IP  - 4
4099  - http://www.ccjm.org/content/92/4/221.short
4100  - http://www.ccjm.org/content/92/4/221.full
SO  - Cleve Clin J Med2025 Apr 01; 92
AB  - Whether subclinical hypothyroidism should be treated in elderly patients (≥ 65 years) is controversial. The authors argue for a personalized, wait-and-see approach rather than universal treatment, pointing out that randomized clinical trials have not shown that levothyroxine treatment makes any difference in terms of hard clinical end points, quality of life, or hypothyroid symptom relief in elderly patients with this condition.