RT Journal Article SR Electronic T1 Most elderly patients with subclinical hypothyroidism do not need to be treated JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 221 OP 231 DO 10.3949/ccjm.92a.24098 VO 92 IS 4 A1 Xu, Risheng A1 Abate, Nicola A1 Ram, Nalini A1 Little, Kristina YR 2025 UL http://www.ccjm.org/content/92/4/221.abstract AB Whether subclinical hypothyroidism should be treated in elderly patients (≥ 65 years) is controversial. The authors argue for a personalized, wait-and-see approach rather than universal treatment, pointing out that randomized clinical trials have not shown that levothyroxine treatment makes any difference in terms of hard clinical end points, quality of life, or hypothyroid symptom relief in elderly patients with this condition.