PT  - JOURNAL ARTICLE
AU  - Mohammad Hassan Pervaiz
AU  - Michael G. Dickinson
AU  - Mohamad Yamani
TI  - Is digoxin a drug of the past?
DP  - 2006 Sep 01
TA  - Cleveland Clinic Journal of Medicine
PG  - 821--834
VI  - 73
IP  - 9
4099  - http://www.ccjm.org/content/73/9/821.short
4100  - http://www.ccjm.org/content/73/9/821.full
SO  - Cleve Clin J Med2006 Sep 01; 73
AB  - Digoxin has been the cornerstone of the treatment of heart failure for more than 2 centuries. Now that newer therapies have been introduced that reduce the mortality rate in heart failure and recent trials have failed to prove the same for digoxin, its use has significantly decreased. But a careful review of the multiple pharmacologic actions of digoxin and closer analysis of the results of recent trials suggest that digoxin may in fact continue to be an effective treatment for heart failure.