PT  - JOURNAL ARTICLE
AU  - Amjad AlMahameed
AU  - John R. Bartholomew
AU  - Amjad AlMahameed
AU  - Deepak L. Bhatt
TI  - Contemporary management of peripheral arterial disease
DP  - 2006 Oct 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S45--S51
VI  - 73
IP  - 10 suppl 4
4099  - http://www.ccjm.org/content/73/10_suppl_4/S45.short
4100  - http://www.ccjm.org/content/73/10_suppl_4/S45.full
SO  - Cleve Clin J Med2006 Oct 01; 73
AB  - Traditional indications for invasive treatment in patients with peripheral arterial disease (PAD) have been salvage of a threatened limb or improvement of functional capacity in cases of disabling intermittent claudication, but advances in interventional therapy may be lowering the threshold for these therapies. Percutaneous transluminal angioplasty (PTA), with or without stent placement, is the most common endovascular intervention in patients with occlusive lower extremity PAD. In general, PTA is best suited to cases of short-segment stenosis or large-bore vessels, whereas surgery is best applied to multilevel occlusions involving smaller and more distant vessels. This article reviews endovascular therapy, catheter-based thrombolysis, and surgical revascularization procedures in patients with PAD, with special attention to recommendations from new American College of Cardiology/American Heart Association guidelines.