PT - JOURNAL ARTICLE AU - Rejeleene, Rick AU - Mehta, Neil B. TI - Artificial intelligence in medicine: How it works, how it fails AID - 10.3949/ccjm.93a.25089 DP - 2026 Feb 01 TA - Cleveland Clinic Journal of Medicine PG - 113--120 VI - 93 IP - 2 4099 - http://www.ccjm.org/content/93/2/113.short 4100 - http://www.ccjm.org/content/93/2/113.full SO - Cleve Clin J Med2026 Feb 01; 93 AB - Artificial intelligence (AI) is transforming healthcare, with large language models emerging as important tools for clinical practice, education, and research. To use it safely and effectively, healthcare professionals need to understand how it works, and how it fails. Using practical clinical examples, the authors explain the subset of AI called large language models, highlighting their capabilities and their limitations.