PT  - JOURNAL ARTICLE
AU  - Amjad AlMahameed
AU  - John R. Bartholomew
AU  - John R. Bartholomew
AU  - Jeffrey W. Olin
TI  - Pathophysiology of peripheral arterial disease and risk factors for its development
DP  - 2006 Oct 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S8--S14
VI  - 73
IP  - 10 suppl 4
4099  - http://www.ccjm.org/content/73/10_suppl_4/S8.short
4100  - http://www.ccjm.org/content/73/10_suppl_4/S8.full
SO  - Cleve Clin J Med2006 Oct 01; 73
AB  - Peripheral arterial disease (PAD) is a systemic atherosclerotic process for which the major risk factors are similar to those for atherosclerosis in the carotid, coronary, and other vascular beds. Among the traditional risk factors for PAD, those with the strongest associations are advanced age, smoking, and diabetes mellitus. More recently, a number of nontraditional risk factors for PAD have also been recognized. This article briefly reviews the pathophysiology of PAD and the evidence supporting established and emerging risk factors for its development.