RT Journal Article
SR Electronic
T1 Pathophysiology of peripheral arterial disease and risk factors for its development
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP S8
OP S14
VO 73
IS 10 suppl 4
A1 AlMahameed, Amjad
A1 Bartholomew, John R.
A1 Bartholomew, John R.
A1 Olin, Jeffrey W.
YR 2006
UL http://www.ccjm.org/content/73/10_suppl_4/S8.abstract
AB Peripheral arterial disease (PAD) is a systemic atherosclerotic process for which the major risk factors are similar to those for atherosclerosis in the carotid, coronary, and other vascular beds. Among the traditional risk factors for PAD, those with the strongest associations are advanced age, smoking, and diabetes mellitus. More recently, a number of nontraditional risk factors for PAD have also been recognized. This article briefly reviews the pathophysiology of PAD and the evidence supporting established and emerging risk factors for its development.