TY - JOUR T1 - The controversy over long-acting beta agonists: Examining the evidence JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 973 LP - 992 VL - 73 IS - 11 AU - David M. Lang Y1 - 2006/11/01 UR - http://www.ccjm.org/content/73/11/973.abstract N2 - In the Salmeterol Multicenter Asthma Research Trial (SMART), patients receiving the long-acting beta agonist salmeterol—particularly African Americans—had a statistically significantly higher risk of fatal or potentially fatal asthma episodes. As a result, medications that contain salmeterol (Serevent, Advair) or formoterol (Foradil) carry a “black box warning.” However, the benefits of these drugs continue to outweigh the risks, if they are used appropriately. ER -