RT Journal Article SR Electronic T1 Diagnosing and treating bipolar disorder in primary care JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 601 OP 608 DO 10.3949/ccjm.85gr.18003 VO 85 IS 8 A1 Parashar Koirala A1 Amit Anand YR 2018 UL http://www.ccjm.org/content/85/8/601.abstract AB Major depression often presents in patients with a history of both depression and mania, although patients may not have the insight to report manic symptoms as problematic. Distinguishing pure (unipolar) depression from bipolar depression is important for prognostic and treatment reasons. Once identified, bipolar depression can be adequately and safely treated.