RT Journal Article
SR Electronic
T1 Beta-cell therapies for type 1 diabetes: Transplants and bionics
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 931
OP 937
DO 10.3949/ccjm.85a.17088
VO 85
IS 12
A1 Kathryn Bux Rodeman
A1 Betul Hatipoglu
YR 2018
UL http://www.ccjm.org/content/85/12/931.abstract
AB Research continues toward the goal of treating type 1 diabetes by replacing insulin-producing beta cells. Ideally, such treatment would be safe and long-lasting and would eliminate the need for subcutaneous insulin replacement. This article reviews the current state of beta-cell replacement through transplant of the whole pancreas or of islet cells. It also looks at the “bionic” pancreas and other future challenges.