RT Journal Article
SR Electronic
T1 Acute cardiorenal syndrome: Mechanisms and clinical implications
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 231
OP 239
DO 10.3949/ccjm.85a.17019
VO 85
IS 3
A1 Guramrinder S. Thind
A1 Mark Loehrke
A1 Jeffrey L. Wilt
YR 2018
UL http://www.ccjm.org/content/85/3/231.abstract
AB Cardiac and renal dysfunction often coexist, and one begets the other. The association is referred to as cardio-renal syndrome. One subtype, acute cardiorenal syndrome, is often described as a clinical scenario in which acute worsening of cardiac function leads to acute kidney injury. Though this definition covers the basic pathophysiologic framework, a robust clinical definition is still lacking. Acute cardiorenal syndrome is common and often leads to emergency room visits and hospitalization. Our understanding of the hemodynamic mechanisms of acute cardiorenal syndrome is advancing. Correction of hypervolemia is the mainstay of therapy.