TY - JOUR T1 - Acute cardiorenal syndrome: Mechanisms and clinical implications JF - Cleveland Clinic Journal of Medicine JO - Cleve Clin J Med SP - 231 LP - 239 DO - 10.3949/ccjm.85a.17019 VL - 85 IS - 3 AU - Guramrinder S. Thind AU - Mark Loehrke AU - Jeffrey L. Wilt Y1 - 2018/03/01 UR - http://www.ccjm.org/content/85/3/231.abstract N2 - Cardiac and renal dysfunction often coexist, and one begets the other. The association is referred to as cardio-renal syndrome. One subtype, acute cardiorenal syndrome, is often described as a clinical scenario in which acute worsening of cardiac function leads to acute kidney injury. Though this definition covers the basic pathophysiologic framework, a robust clinical definition is still lacking. Acute cardiorenal syndrome is common and often leads to emergency room visits and hospitalization. Our understanding of the hemodynamic mechanisms of acute cardiorenal syndrome is advancing. Correction of hypervolemia is the mainstay of therapy. ER -