RT Journal Article
SR Electronic
T1 Alzheimer dementia: Starting, stopping drug therapy
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 209
OP 214
DO 10.3949/ccjm.85a.16080
VO 85
IS 3
A1 Kim, Luke D.
A1 Factora, Ronan M.
YR 2018
UL http://www.ccjm.org/content/85/3/209.abstract
AB Alzheimer disease is the most common type of dementia. Two classes of cognition-enhancing drugs are approved to treat the symptoms, and both have provided modest benefit in clinical trials. Psychotropic drugs are sometimes used off-label to treat behavioral symptoms of Alzheimer disease. All these medications should be continuously evaluated for clinical efficacy and, when appropriate, discontinued if the primary benefit—preservation of cognitive and functional status and a reduction in behaviors associated with dementia—is no longer being achieved.