PT - JOURNAL ARTICLE AU - Tavee, Jinny O. TI - Office approach to small fiber neuropathy AID - 10.3949/ccjm.85a.17124 DP - 2018 Oct 01 TA - Cleveland Clinic Journal of Medicine PG - 801--812 VI - 85 IP - 10 4099 - http://www.ccjm.org/content/85/10/801.short 4100 - http://www.ccjm.org/content/85/10/801.full SO - Cleve Clin J Med2018 Oct 01; 85 AB - Small fiber neuropathy is often characterized by neuropathic pain in the feet with normal nerve conduction studies and neurologic examination. Diagnosis requires specialized nerve tests, including autonomic studies and a skin biopsy study showing reduced intraepidermal nerve fiber density. Small fiber neuropathy has numerous causes but is often idiopathic. A practical approach to identifying an underlying cause is to first screen for common ones and then proceed with further testing as needed. Treatment consists of correcting the underlying cause, managing pain, and modifying lifestyle.