RT Journal Article SR Electronic T1 Office approach to small fiber neuropathy JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 801 OP 812 DO 10.3949/ccjm.85a.17124 VO 85 IS 10 A1 Jinny O. Tavee YR 2018 UL http://www.ccjm.org/content/85/10/801.abstract AB Small fiber neuropathy is often characterized by neuropathic pain in the feet with normal nerve conduction studies and neurologic examination. Diagnosis requires specialized nerve tests, including autonomic studies and a skin biopsy study showing reduced intraepidermal nerve fiber density. Small fiber neuropathy has numerous causes but is often idiopathic. A practical approach to identifying an underlying cause is to first screen for common ones and then proceed with further testing as needed. Treatment consists of correcting the underlying cause, managing pain, and modifying lifestyle.