RT Journal Article SR Electronic T1 Parsimonious blood use and lower transfusion triggers: What is the evidence? JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 43 OP 51 DO 10.3949/ccjm.84a.15134 VO 84 IS 1 A1 Auron, Moises A1 Castillo, Marina Y. Duran A1 Kumar, Ajay YR 2017 UL http://www.ccjm.org/content/84/1/43.abstract AB Evidence supports a parsimonious approach to blood use for managing anemia, contrasting with the long-standing practice of blood transfusion targeting arbitrary hemoglobin levels. Hemodilution studies have demonstrated that humans can tolerate anemia. The cumulative data have confirmed and validated the safety of a conservative approach to transfusion. This has translated into formal national guidelines for blood transfusion as well as patient safety and quality markers supporting blood management stewardship to minimize unnecessary use of blood products.