PT - JOURNAL ARTICLE AU - Vania Modesto-Lowe AU - Katie Swiezbin AU - Margaret Chaplin AU - Gabriela Hoefer TI - Use and misuse of opioid agonists in opioid addiction AID - 10.3949/ccjm.84a.16091 DP - 2017 May 01 TA - Cleveland Clinic Journal of Medicine PG - 377--384 VI - 84 IP - 5 4099 - http://www.ccjm.org/content/84/5/377.short 4100 - http://www.ccjm.org/content/84/5/377.full SO - Cleve Clin J Med2017 May 01; 84 AB - Although methadone (an opioid agonist) and buprenorphine (a partial opioid agonist) have evidence to support their use in treating opioid use disorder, they remain misunderstood and underutilized. In this article, we outline the risks and benefits of using these drugs as maintenance therapy in opioid-dependent patients.