RT Journal Article SR Electronic T1 Autosomal dominant polycystic kidney disease and the heart and brain JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 471 OP 481 DO 10.3949/ccjm.84a.16107 VO 84 IS 6 A1 Vinod Krishnappa A1 Poornima Vinod A1 Divya Deverakonda A1 Rupesh Raina YR 2017 UL http://www.ccjm.org/content/84/6/471.abstract AB Autosomal dominant polycystic kidney disease (ADPKD) has numerous systemic manifestations and complications. This article gives an overview of hypertension, cardiac complications, and intracranial aneurysms in ADPKD, their pathophysiology, and recent developments in their management.