PT - JOURNAL ARTICLE AU - Heather D. Hirsch AU - Elim Shih AU - Holly L. Thacker TI - ERAAs for menopause treatment: Welcome the ‘designer estrogens’ AID - 10.3949/ccjm.84a.15140 DP - 2017 Jun 01 TA - Cleveland Clinic Journal of Medicine PG - 463--470 VI - 84 IP - 6 4099 - http://www.ccjm.org/content/84/6/463.short 4100 - http://www.ccjm.org/content/84/6/463.full SO - Cleve Clin J Med2017 Jun 01; 84 AB - Estrogen receptor agonist-antagonists (ERAAs) selectively inhibit or stimulate estrogen-like action in targeted tissues. This review summarizes how ERAAs can be used in combination with an estrogen or alone to treat menopausal symptoms (vasomotor symptoms, genitourinary syndrome of menopause), breast cancer or the risk of breast cancer, osteopenia, osteoporosis, and other female midlife concerns.