RT Journal Article SR Electronic T1 ERAAs for menopause treatment: Welcome the ‘designer estrogens’ JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 463 OP 470 DO 10.3949/ccjm.84a.15140 VO 84 IS 6 A1 Hirsch, Heather D. A1 Shih, Elim A1 Thacker, Holly L. YR 2017 UL http://www.ccjm.org/content/84/6/463.abstract AB Estrogen receptor agonist-antagonists (ERAAs) selectively inhibit or stimulate estrogen-like action in targeted tissues. This review summarizes how ERAAs can be used in combination with an estrogen or alone to treat menopausal symptoms (vasomotor symptoms, genitourinary syndrome of menopause), breast cancer or the risk of breast cancer, osteopenia, osteoporosis, and other female midlife concerns.