RT Journal Article
SR Electronic
T1 Chronic kidney disease in African Americans: Puzzle pieces are falling into place
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 855
OP 862
DO 10.3949/ccjm.84gr.17007
VO 84
IS 11
A1 Nally, Joseph V.
YR 2017
UL http://www.ccjm.org/content/84/11/855.abstract
AB Recent decades have seen great advances in the understanding of chronic kidney disease, spurred by standardizing disease definitions and large-scale patient surveillance. African Americans are disproportionately affected by the disease, and recently discovered genetic variants in APOL1 that protect against sleeping sickness in Africa provide an important explanation for the increased burden. Studies are now under way to determine if genetic testing of African American transplant donors and recipients is advisable.