RT Journal Article
SR Electronic
T1 Cardiac amyloidosis: An update on diagnosis and treatment
JF Cleveland Clinic Journal of Medicine
JO Cleve Clin J Med
FD Cleveland Clinic
SP 12
OP 26
DO 10.3949/ccjm.84.s3.02
VO 84
IS 12 suppl 3
A1 Joseph P. Donnelly
A1 Mazen Hanna
YR 2017
UL http://www.ccjm.org/content/84/12_suppl_3/12.abstract
AB Cardiac amyloidosis (CA), once thought to be a rare disease, is increasingly recognized due to enhanced clinical awareness and better diagnostic imaging. CA is becoming of heightened interest to the cardiology community given more effective treatment strategies for light chain amyloidosis (AL), as well as emerging therapies for transthyretin amyloidosis (ATTR). Furthermore, reversing amyloid deposition in affected organs using monoclonal antibodies is actively being tested in clinical trials. A high index of suspicion and a systematic approach to the diagnosis of CA can lead to referral to a center of expertise for timely treatment.