PT - JOURNAL ARTICLE AU - Siamak Moghadam-Kia AU - Chester V. Oddis AU - Rohit Aggarwal TI - Approach to asymptomatic creatine kinase elevation AID - 10.3949/ccjm.83a.14120 DP - 2016 Jan 01 TA - Cleveland Clinic Journal of Medicine PG - 37--42 VI - 83 IP - 1 4099 - http://www.ccjm.org/content/83/1/37.short 4100 - http://www.ccjm.org/content/83/1/37.full SO - Cleve Clin J Med2016 Jan 01; 83 AB - How to manage a patient who has an elevated serum creatine kinase (CK) level but no or insignificant muscle-related signs and symptoms is a clinical conundrum. The authors provide a systematic approach, including repeat testing after a period of rest, defining higher thresholds over which pursuing a diagnosis is worthwhile, and evaluating for a variety of nonneuromuscular causes. They also outline a workup for neuromuscular causes.