RT Journal Article SR Electronic T1 Advances in the treatment of dyslipidemia JF Cleveland Clinic Journal of Medicine JO Cleve Clin J Med FD Cleveland Clinic SP 181 OP 186 DO 10.3949/ccjm.83gr.16001 VO 83 IS 3 A1 Sabatine, Marc S. YR 2016 UL http://www.ccjm.org/content/83/3/181.abstract AB Although current guidelines do not set specific targets for lowering levels of low-density lipoprotein cholesterol (LDL-C), several lines of evidence support the concept that "lower is better." Statin drugs in combination with new agents now make it possible to lower LDL-C to new lows. Determining the risk of cardiovascular disease in apparently healthy adults and how far to extend treatment for primary prevention has critical implications for public health.