PT - JOURNAL ARTICLE AU - Umur S. Hatipoglu AU - Loutfi S. Aboussouan TI - Treating and preventing acute exacerbations of COPD AID - 10.3949/ccjm.83a.14188 DP - 2016 Apr 01 TA - Cleveland Clinic Journal of Medicine PG - 289--300 VI - 83 IP - 4 4099 - http://www.ccjm.org/content/83/4/289.short 4100 - http://www.ccjm.org/content/83/4/289.full SO - Cleve Clin J Med2016 Apr 01; 83 AB - Acute exacerbations of chronic obstructive pulmonary disease (COPD)—characterized by shortness of breath, increased sputum production, increased purulence, or a combination of these signs—are costly and can have major impacts on the patient’s health. Corticosteroids, antibiotics, and bronchodilators are the cornerstones of prevention and therapy, with mucolytics, oxygen supplementation, and ventilatory support also advisable for some patients. Treatment should be evidence-based and tailored to the patient’s history and present needs.