PT  - JOURNAL ARTICLE
AU  - Meneghini, Luigi
TI  - New insulin preparations: A primer for the clinician
AID  - 10.3949/ccjm.83.s1.05
DP  - 2016 May 01
TA  - Cleveland Clinic Journal of Medicine
PG  - S27--S33
VI  - 83
IP  - 5 suppl 1
4099  - http://www.ccjm.org/content/83/5_suppl_1/S27.short
4100  - http://www.ccjm.org/content/83/5_suppl_1/S27.full
SO  - Cleve Clin J Med2016 May 01; 83
AB  - The importance of glycemic control in preventing the chronic and devastating complications of diabetes is well established. Insulin administration is an important therapeutic option for managing diabetes, particularly for patients with profound insulin deficiency. Many insulin formulations are on the market, including short-acting insulin analogues, inhaled insulin, concentrated insulin, and basal insulin. Each category has a unique onset, peak, and duration of action. This article reviews the differing pharmacokinetic and pharmacodynamic properties and safety and efficacy data, and discusses the implications for clinical practice.